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What is esr?

ESR: ESR measures how quickly red blood cells settle in a tube, indirectly indicating inflammation. Elevated in inflammatory arthritis, infections, and other conditions. Used alongside CRP to monitor disease activity, not for diagnosis alone.

ESR (erythrocyte sedimentation rate) measures how quickly red blood cells settle to the bottom of a thin tube in one hour. Inflammation makes them stick together and fall faster, so a raised ESR is a general marker of inflammation, infection or some cancers. Rheumatology teams use it alongside CRP to gauge how active a disease like polymyalgia rheumatica, giant cell arteritis or rheumatoid arthritis is, and to track response to treatment. It rises and falls more slowly than CRP.

Last updated 2026-07-04. This is general information, not a substitute for personalised medical advice.

Sources and references

  1. NHS: Arthritis overview
  2. NICE guidance

Sources and further reading