NSAID stands for Non-Steroidal Anti-Inflammatory Drug. This family — ibuprofen, naproxen, diclofenac, etoricoxib and others — reduces pain, swelling and stiffness by blocking COX enzymes that produce inflammatory prostaglandins. NSAIDs are widely used in osteoarthritis, gout flares and inflammatory arthritis, either as tablets, topical gels or by injection. Because they can irritate the stomach and raise blood-pressure or kidney-injury risk, UK guidance recommends the lowest effective dose for the shortest time, often with a stomach-protecting drug (PPI) for people over 45 or on long courses.
What is nsaid?
NSAID: NSAIDs reduce pain and inflammation but carry stomach, kidney and heart risk with sustained use. NICE recommends topical NSAIDs first for hand/knee OA. Take with food; check with pharmacist if over 65, taking blood thinners, or with kidney/heart conditions.
Last updated 2026-07-04. This is general information, not a substitute for personalised medical advice.