Overview
Naproxen is well-tolerated by many people, but like all NSAIDs, it can cause side effects. The risk of side effects increases with higher doses and longer duration of use. This guide covers the most important side effects to be aware of.
Common Side Effects (affect more than 1 in 100 people)
- Indigestion and heartburn
- Stomach pain or discomfort
- Nausea
- Constipation or diarrhoea
- Headache
- Dizziness
- Drowsiness
Serious Side Effects (seek medical advice promptly)
- Stomach ulcer — symptoms include persistent stomach pain, indigestion that doesn't improve, and loss of appetite
- Gastrointestinal bleeding — dark, tarry, or bloody stools; vomiting blood (coffee-ground appearance) — seek emergency help immediately
- Allergic reaction — rash, swelling of the face, lips, or throat, difficulty breathing — seek emergency help
- Kidney problems — reduced urine output, swollen ankles, unusual tiredness
- Liver problems — yellowing of skin or eyes (jaundice)
- Heart attack or stroke symptoms — chest pain, sudden severe headache, facial drooping, arm weakness — call 999
How to Reduce Side Effect Risk
- Always take with food or milk
- Use the lowest effective dose for the shortest time
- Take a stomach-protecting medicine (PPI) if prescribed
- Avoid alcohol
- Stay hydrated
- Inform your doctor of all other medications